Kimwe mu byiza by'ingenzi by'ibikoresho bya ePTFE ni uko birushaho gukomera ugereranije na PTFE ikomeye. Ubu buryo bworoshye butuma ihuzwa neza cyane n'ubuso butaringaniye, bwacitse cyangwa bwangiritse, bigatuma ifunga neza kandi yizewe nubwo haba hari imitwaro mike y'amaboliti. Iki kimenyetso kigabanya amahirwe yo kuva amazi akenshi ahura n'ibikoresho bidahuye neza n'ubuso butaringaniye. Byongeye kandi, imiterere ya ePTFE igabanya cyane ibibazo byo gucika intege (guhinduka kw'imiterere y'ibikoresho mu gihe cy'umutwaro uhoraho) n'ubukonje (gusohoka kw'ibikoresho mu gihe cy'umuvuduko mu bushyuhe bw'ikirere), ibyo bikaba ari imbogamizi zisanzwe za PTFE isanzwe. Uku guhagarara neza mu rugero rwiza gutuma agapapuro kagumaho kandi karamba mu gihe kirekire kandi mu bihe bitandukanye by'imikorere.
Kuba ifite ubushobozi bwo gukora ibintu byinshi bituma ePTFE iba igisubizo cy’umwuka rusange mu muryango wa PTFE, gishobora gusimbuza gasket za PTFE zikozwe mu buryo bwa "skilled", "zuzuye", cyangwa "enflake" mu bikorwa byinshi. Ubuhanga bwayo budasanzwe bwo kudakora neza kw’imiti, bwarazwe na PTFE idakora neza, bivuze ko irwanya ibitero by’imiti hafi ya yose mu bushyuhe bwinshi, bigatuma ikwiriye ahantu hanini ho gukwirakwiza amakuru. Byongeye kandi, kuba iyi mashini ikurikiza amabwiriza ya FDA (nka 21 CFR 177.1550) byemeza ko ikwiriye gukoreshwa mu buryo bw’ibanga burimo gukora ku biribwa, ibinyobwa, n’imiti.
Yunganira ifishi y'urupapuro, Expanded PTFE Joint Sealant, ikunze gutangwa nk'ikaseti cyangwa umugozi woroshye ufite agakoresho kometseho, itanga inyungu zisa ariko mu buryo bwa gasket. Iyi kaseti yo gufunga ni nziza mu gufunga uduce duto, tugoye, cyangwa tutari dusanzwe aho gukata gasket y'urupapuro bidashoboka cyangwa ngo bipfushe ubusa. Ihuye byoroshye n'imiterere igoye kandi itanga agasanduku kizewe gafite ubushobozi bwo kurwanya imiti, kwihanganira ubushyuhe, no kugabanuka kw'imiterere nk'impapuro za ePTFE, bigatuma byombi bikora ibisubizo byo gufunga bifite imikorere myiza yo gukoresha mu nganda.
